|Patchwork: Bioinformatic tool for allele-specific copynumber analysis of tumor samples
Patchwork is a bioinformatic tool for analyzing and visualizing allele-specific copy numbers and loss-of-heterozygosity in cancer genomes. The data input is in the format of whole-genome sequencing data which enables characterization of genomic alterations ranging in size from point mutations to entire chromosomes. High quality results are obtained even if samples have low coverage, ~4x, low tumor cell content or are aneuploid.
Patchwork is available for two data types. Patchwork takes BAM files as input whereas PatchworkCG takes input from CompleteGenomics files.
|Sebastian DiLorenzo (UPPMAX)